Who We Are:
We are interested in using a combination of behavioral, electrophysiological and imaging techniques to understand the mechanisms of neurovascular coupling that maintain a tight relationship between neuronal activity and cerebral blood flow. This relationship is crucial for the brain, and its disruption leads to dysfunction and disease. Our main research interests are in understanding mechanisms of cerebrovascular dysfunction as a common cause of several neurodegenerative diseases.
We have extensive experience in the development and application of multimodal neuroimaging methods to study the brain’s anatomy and function. Our lab works with genetically engineered marmoset models of brain diseases, including Stroke, Alzheimer’s Disease and Multiple Sclerosis.
Our expertise is in the development of functional neuroimaging methods to understand (1) how the cerebral microvasculature reacts, in space and time, to changes in neuronal activity; and (2) to understand how the mechanisms of neurovascular coupling are disrupted in neurological disorders.